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 ### CCP4 4.2: Scala              version 4.2       :         ##
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 User: wgscott  Run date:  4/ 3/04  Run time:14:32:34


 Please reference: Collaborative Computational Project, Number 4. 1994.
 "The CCP4 Suite: Programs for Protein Crystallography". Acta Cryst. D50, 760-763.

 as well as any specific reference in the program write-up.




Input commands:
Table of contents of logfile:


                *******************************************
                *    SCALA - continuous scaling program   *
                *                                         *
                *    Version: 3.1.20                      *
                *    Date   : 6/11/2002                   *
                *                                         *
                *   Phil Evans, MRC LMB, Cambridge, UK    *
                *   pre@mrc-lmb.cam.ac.uk                 *
                *                                         *
                *******************************************


"Scala" P.R.Evans (1997), Joint CCP4 and ESF-EACBM Newsletter 33, 22-24


  (Q)QOPEN: file opened on unit  1      Status: READONLY

 Logical Name: HKLIN      Filename: native_sars_sort_p6522.mtz


 HEADER INFORMATION FROM INPUT MTZ FILE ON INDEX  1
 
 * Title:
 
 native SARS michael robertson's raxis II data..
 
 * Number of Datasets =   1
 
 * Dataset ID, project/crystal name, dataset name, cell dimensions, wavelength:
 
        1 Unspecified /
          Unspecified
             94.0378   94.0378  130.2772   90.0000   90.0000  120.0000
             1.54180
 
 * Number of Columns =  18
 
 * Number of Reflections = 266171
 
 * Missing value set to NaN in input mtz  file
 
 * Number of Batches = 155
 
 * Column Labels :
 
 H K L M/ISYM BATCH I SIGI IPR SIGIPR FRACTIONCALC XDET YDET ROT WIDTH LP MPART
 FLAG BGPKRATIOS
 
 * Column Types :
 
 H H H Y B J Q J Q R R R R R R I I R
 
 * Cell Dimensions :
 
    94.0378   94.0378  130.2772   90.0000   90.0000  120.0000
 
 *  Resolution Range :
 
      0.00051     0.12791      (   44.281 -     2.796 A )
 
 * Sort Order :
 
      1     2     3     4     5
 
 * Space group = P6522  (number   179)
 
 * Input Program Labels :
 
 H K L M/ISYM BATCH I SIGI IPR SIGIPR SCALE SIGSCALE TIME XDET YDET ROT SIGIC
 SIGIPRC MPART FRACTIONCALC FLAG LP IMEAN SIGIMEAN ISUM SIGISUM
 
 * Input File Labels :
 
 H K L M/ISYM BATCH I SIGI IPR SIGIPR FRACTIONCALC XDET YDET ROT WIDTH LP MPART
 FLAG BGPKRATIOS
 
 * Lookup Table : the number indicates the input column no.
 * Array element n corresponds to the nth program label
 
     1    2    3    4    5    6    7    8    9    0    0    0   11   12   13
     0    0   16   10   17   15    0    0    0    0
 
 
           Reciprocal space symmetry
     Space group: P6522 (179)     Point group: 622     Laue group: 6/mmm
 Asymmetric unit: [6/mmm] hkl:h>=0, k>=0, l>=0 with h>=k
 
 Original indices for reflection hkl with symmetry number ISYM
 
                              Bijvoet positive
       ISYM              ISYM              ISYM              ISYM
  ISYM   1  +h,+k,+l       7  -h,-k,+l      13  +k,+h,-l      19  -k,-h,-l
  ISYM   3  -h-k,+h,+l     9  +h+k,-h,+l    15  +h,-h-k,-l    21  -h,+h+k,-l
  ISYM   5  +k,-h-k,+l    11  -k,+h+k,+l    17  -h-k,+k,-l    23  +h+k,-k,-l
 
                              Bijvoet negative
       ISYM              ISYM              ISYM              ISYM
  ISYM   2  -h,-k,-l       8  +h,+k,-l      14  -k,-h,+l      20  +k,+h,+l
  ISYM   4  +h+k,-h,-l    10  -h-k,+h,-l    16  -h,+h+k,+l    22  +h,-h-k,+l
  ISYM   6  -k,+h+k,-l    12  +k,-h-k,-l    18  +h+k,-k,+l    24  -h-k,+k,+l
 
 Data line--- run 1 all
 Data line--- intensities partials # we have few fulls
 Data line--- cycles 40
 Comment line--- # resolution 19.75 2.9
 Data line--- anomalous off           # this is a native set
 Comment line--- #sdcorrection NOADJUST full 5.0 0.00 part 7.0 0.00
 Comment line--- #sdcorrection 1.0 0.00   # from a previous run
 Comment line--- # try it with and without the tails correction: this is with
 Data line--- scales   rotation spacing 10  bfactor ANISOTROPIC
 Comment line--- # tails
 Comment line--- #reject larger
 Comment line--- #reject 2  # reject outliers more than 3sd from mean
 Comment line--- #exclude eprob 1e-8    # reject very large observations, if probability
 Comment line---                            #    .lt. 10**-8  (== Emax 4.3)

Input keyworded commands (click for documentation):

RUN 1 all INTENSITIES partials # we have few fulls CYCLES 40 ANOMALOUS off # this is a native set SCALES rotation spacing 10 bfactor ANISOTROPIC

Contents



 Run number    1 consists of batches :-
       1      2      3      4      5      6      7      8      9     10     11     12     13     14     15     16
      17     18     19     20     21     22     23     24     25     26     27     28     29     30     31     32
      33     34     35     36     37     38     39     40     41     42     43     44     45     46     47     48
      49     50     51     52     53     54     55     56     57     58     59     60     61     62     63     64
      65     66     67     68     69     70     71     72     73     74     75     76     77     78     79     80
      81     82     83     84     85     86     87     88     89     90     91     92     93     94     95     96
      97     98     99    100    101    102    103    104    105    106    107    108    109    110    111    112
     113    114    115    116    117    118    119    120    121    122    123    124    125    126    127    128
     129    130    131    132    133    134    135    136    137    138    139    140    141    142    143    144
     145    146    147    148    149    150    151    152    153    154    155

===== Dataset: Unspecified//Unspecified
     Run(s):    1

> Wavelength and cell extracted from Batch headers, with rms variation:
> Wavelength:  1.541800  Cell:     92.994    92.994   128.869    90.000    90.000   120.000
>              0.000000             0.303     0.303     0.817     0.000     0.000     0.000
 WARNING: some batches have different cells
  Wavelength:  1.541800  Cell:     94.038    94.038   130.277    90.000    90.000   120.000

 PROFILE_FITTED intensities will be used


 Fully-recorded and summed partial reflections will be used in scaling

     Summed partials will be checked for consistent MPART flags
     Maximum number of parts in summed partials equivalent to 5.0 degrees
     Summed partials accepted for scaling if total fraction lies between   0.950 and   1.050
     Partials with missing parts in the middle will be rejected

 Overall resolution limits:    44.2807    2.7961



 In solving least-squares equations:-
                      Eigenvalue filter limit:    0.000001
                     No damping of shifts


 At least TWO eigenvalues will be filtered


 VARIANCE weights will be used in scaling

                   Smoothing factors   Maximum fractional distance
             Time:        0.50                  3.0000
         Rotation:        1.00                  3.0000
         Detector:        1.00                  3.0000


   Reflections will be excluded from scaling in all runs if:

     I .lt. sd(I) *      3.000

 Reflections judged implausibly large will be rejected from scaling and merging
     Maximum normalised F (ie E) for acentric reflection    10.000
     Maximum normalised F (ie E) for centric reflection     12.000
     Minimum probability before reflection is rejected   0.378E-43


 Outlier rejection limits
 ========================

 --| In scaling |--
   ==== For all observations including I+ & I-  ====
    Reflections measured 3 or more times:     6.000   maximum deviation from weighted mean of all other observations
    Reflections measured twice:     6.000   maximum deviation from weighted mean
          2   first refinement cycle to reject outliers

 --| In merging |--
    Reflections measured 3 or more times:     6.000   maximum deviation from weighted mean of all other observations
    Reflections measured twice:     6.000   maximum deviation from weighted mean


 Standard deviations will be adjusted to SdFac * Sqrt[sd(I)**2 + SdB I + (SdAdd I)**2] as follows:-
                        Fulls                          Partials
        Run    SdFac       SdB     SdAdd        SdFac      SdB      SdAdd

          1   1.00000   0.00000   0.02000      1.00000   0.00000   0.02000



 Layout of scale factors
 =======================


 Run number    1    Dataset: Unspecified//Unspecified

 Relative B-factor:    17 factors at intervals of    10.00 on rotation
     Anisotropic B-factors
 Scales:
     Along rotation axis:    17 scales at intervals of    10.00
     No variation of scale with detector coordinate

 ===========================================



 Working array size =         71



 Matrix of number of overlaps between rotation ranges for each run,
  for reflection observations which will be used for scaling
 Each group is labelled "run_number.range"

 Note that the number of ranges is one less than the number of scale factors








 Initial scales for run     1
     1.0000    0.9672    0.9563    0.9579    0.9383    0.8833    0.8168    0.7710    0.6840    0.6283
     0.6280    0.6195    0.6196    0.6310    0.6342    0.6247    0.6013





  =====  Cycle     1  =====
 Residual Sum( w Del**2) =      0.839E+06, restraint residual =       0.00    , total residual =       0.119E+07
 Sum( w Del**2) / (m-n) =       10.81    
    2 eigenvalues filtered out, smallest =  -0.528E-10, smallest filtered =    0.760E-07   Damping factor =   0.000
    77687 observations used from     4543 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
                0    outliers


 Mean and maximum shift/sd :      5.405    20.936 (parameter    66   K1.15.1 )



=== Shifts for cycle    1


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 Shift    :     0.443    -0.624    -1.750     1.274    -0.473     0.377     1.484    -0.759     0.171     1.798
 New value:     0.443    -0.624    -1.750     1.274    -0.473     0.377     1.484    -0.759     0.171     1.798
 Error    :     0.205     0.109     0.212     0.156     0.083     0.159     0.164     0.083     0.148     0.171
 Number   :      6162      6162      6162     11273     11273     11273     12258     12258     12258     11616

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 Shift    :    -0.018     0.644     2.412    -0.104     0.555     2.161    -0.212     0.586     2.329     0.035
 New value:    -0.018     0.644     2.412    -0.104     0.555     2.161    -0.212     0.586     2.329     0.035
 Error    :     0.086     0.148     0.172     0.086     0.149     0.171     0.085     0.147     0.169     0.082
 Number   :     11616     11616     11387     11387     11387     11313     11313     11313     11251     11251

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 Shift    :     0.482     1.944    -0.733    -0.022     0.819    -0.773    -0.333     1.473    -0.206    -0.382
 New value:     0.482     1.944    -0.733    -0.022     0.819    -0.773    -0.333     1.473    -0.206    -0.382
 Error    :     0.145     0.169     0.082     0.148     0.160     0.080     0.150     0.148     0.076     0.141
 Number   :     11251     11395     11395     11395     11512     11512     11512     11935     11935     11935

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 Shift    :     0.852    -0.013     0.150     0.396    -0.128     0.152     0.723    -0.259     0.451     0.444
 New value:     0.852    -0.013     0.150     0.396    -0.128     0.152     0.723    -0.259     0.451     0.444
 Error    :     0.137     0.073     0.140     0.132     0.071     0.139     0.129     0.072     0.137     0.134
 Number   :     12389     12389     12389     12923     12923     12923     13409     13409     13409     13689

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 Shift    :    -0.094     0.211     0.559     0.068     0.229     0.608     0.002     0.424     0.232     0.189
 New value:    -0.094     0.211     0.559     0.068     0.229     0.608     0.002     0.424     0.232     0.189
 Error    :     0.072     0.141     0.132     0.078     0.144     0.181     0.098     0.208     0.539     0.315
 Number   :     13689     13689     13648     13648     13648      9418      9418      9418      3870      3870

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:     0.000     1.000     0.967     0.956     0.958     0.938     0.883     0.817     0.771     0.684
 Shift    :     0.319     0.000    -0.027     0.042     0.204     0.180     0.191     0.091     0.085     0.051
 New value:     0.319     1.000     0.940     0.999     1.162     1.118     1.074     0.908     0.856     0.735
 Error    :     0.644     0.016     0.015     0.017     0.023     0.021     0.021     0.015     0.015     0.012
 Number   :      3870      8850     13688     17156     16634     16144     16020     15955     16104     16332

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.628     0.628     0.619     0.620     0.631     0.634     0.625     0.601
 Shift    :    -0.066    -0.011    -0.084    -0.091    -0.125    -0.140    -0.139    -0.144
 New value:     0.562     0.617     0.536     0.529     0.506     0.494     0.486     0.457
 Error    :     0.007     0.009     0.007     0.007     0.007     0.007     0.010     0.013
 Number   :     16851     17438     18251     18809     19171     17853     12250      6665

 FORMATTED      UNKNOWN file opened on unit   1

 Logical name: SCALES, Filename: SCALES




  =====  Cycle     2  =====
 Residual Sum( w Del**2) =      0.165E+06, restraint residual =       0.00    , total residual =       0.465E+06
 Sum( w Del**2) / (m-n) =       2.477    
    2 eigenvalues filtered out, smallest =  -0.218E-09, smallest filtered =    0.757E-07   Damping factor =   0.000
    66591 observations used from     3944 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              599    outliers


 Mean and maximum shift/sd :      2.149     5.894 (parameter    61   K1.10.1 )



=== Shifts for cycle    2


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.443    -0.624    -1.750     1.274    -0.473     0.377     1.484    -0.759     0.171     1.798
 Shift    :     0.400     0.042     0.736    -0.080    -0.047     0.185    -0.247    -0.089     0.342     0.384
 New value:     0.843    -0.582    -1.014     1.194    -0.520     0.562     1.236    -0.848     0.514     2.182
 Error    :     0.117     0.069     0.127     0.084     0.049     0.089     0.087     0.049     0.085     0.093
 Number   :      4885      4885      4885      9159      9159      9159     10250     10250     10250     10020

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:    -0.018     0.644     2.412    -0.104     0.555     2.161    -0.212     0.586     2.329     0.035
 Shift    :     0.058    -0.166     0.170     0.032    -0.377     0.416     0.079    -0.150     0.199     0.040
 New value:     0.040     0.478     2.582    -0.072     0.179     2.577    -0.133     0.436     2.528     0.075
 Error    :     0.051     0.087     0.091     0.051     0.086     0.089     0.049     0.085     0.086     0.046
 Number   :     10020     10020     10004     10004     10004     10117     10117     10117     10063     10063

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.482     1.944    -0.733    -0.022     0.819    -0.773    -0.333     1.473    -0.206    -0.382
 Shift    :    -0.089     0.207     0.073    -0.182     0.229     0.095     0.172     0.040     0.106     0.270
 New value:     0.393     2.151    -0.659    -0.204     1.048    -0.678    -0.161     1.513    -0.100    -0.112
 Error    :     0.082     0.086     0.047     0.084     0.082     0.046     0.083     0.075     0.042     0.076
 Number   :     10063     10075     10075     10075      9974      9974      9974     10064     10064     10064

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.852    -0.013     0.150     0.396    -0.128     0.152     0.723    -0.259     0.451     0.444
 Shift    :     0.011    -0.048     0.156     0.102    -0.038     0.254    -0.091    -0.036     0.150    -0.092
 New value:     0.864    -0.061     0.305     0.499    -0.167     0.406     0.632    -0.295     0.600     0.352
 Error    :     0.070     0.040     0.074     0.068     0.038     0.072     0.065     0.037     0.069     0.065
 Number   :     10292     10292     10292     10673     10673     10673     11294     11294     11294     11849

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.094     0.211     0.559     0.068     0.229     0.608     0.002     0.424     0.232     0.189
 Shift    :    -0.064     0.151     0.026    -0.053     0.082     0.034     0.046     0.030     0.037    -0.126
 New value:    -0.157     0.363     0.585     0.015     0.311     0.642     0.047     0.454     0.269     0.063
 Error    :     0.036     0.070     0.064     0.039     0.072     0.086     0.048     0.103     0.258     0.154
 Number   :     11849     11849     12001     12001     12001      8278      8278      8278      3415      3415

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:     0.319     1.000     0.940     0.999     1.162     1.118     1.074     0.908     0.856     0.735
 Shift    :    -0.405     0.000     0.043     0.016     0.041    -0.008     0.033     0.017     0.020     0.023
 New value:    -0.087     1.000     0.984     1.015     1.203     1.110     1.107     0.924     0.876     0.758
 Error    :     0.309     0.009     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3415      7114     11235     14330     14327     14213     14235     14214     14230     14089

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.562     0.617     0.536     0.529     0.506     0.494     0.486     0.457
 Shift    :     0.023     0.024     0.022     0.020     0.009     0.010     0.007     0.007
 New value:     0.586     0.641     0.558     0.549     0.515     0.503     0.493     0.464
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.008
 Number   :     14264     14500     15187     15933     16520     15649     10781      5869


  =====  Cycle     3  =====
 Residual Sum( w Del**2) =      0.160E+06, restraint residual =       0.00    , total residual =       0.459E+06
 Sum( w Del**2) / (m-n) =       2.413    
    2 eigenvalues filtered out, smallest =   0.225E-09, smallest filtered =    0.752E-07   Damping factor =   0.000
    66247 observations used from     3928 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              615    outliers


 Mean and maximum shift/sd :      0.514     1.987 (parameter    53   K1.2.1  )



=== Shifts for cycle    3


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.843    -0.582    -1.014     1.194    -0.520     0.562     1.236    -0.848     0.514     2.182
 Shift    :     0.086     0.120     0.096    -0.062    -0.007     0.172    -0.076    -0.013    -0.048     0.009
 New value:     0.929    -0.462    -0.918     1.132    -0.527     0.734     1.160    -0.861     0.466     2.191
 Error    :     0.114     0.066     0.123     0.084     0.049     0.088     0.087     0.048     0.084     0.091
 Number   :      4834      4834      4834      9063      9063      9063     10147     10147     10147      9954

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.040     0.478     2.582    -0.072     0.179     2.577    -0.133     0.436     2.528     0.075
 Shift    :     0.011     0.005    -0.019     0.005    -0.057     0.015    -0.019     0.002     0.004     0.003
 New value:     0.051     0.483     2.563    -0.067     0.122     2.592    -0.152     0.438     2.532     0.078
 Error    :     0.050     0.087     0.089     0.050     0.085     0.088     0.049     0.084     0.085     0.046
 Number   :      9954      9954      9966      9966      9966     10079     10079     10079     10027     10027

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.393     2.151    -0.659    -0.204     1.048    -0.678    -0.161     1.513    -0.100    -0.112
 Shift    :    -0.016    -0.011     0.003    -0.025     0.012     0.017     0.005    -0.015     0.027    -0.019
 New value:     0.377     2.140    -0.656    -0.229     1.060    -0.661    -0.155     1.498    -0.073    -0.131
 Error    :     0.081     0.085     0.047     0.083     0.081     0.045     0.082     0.075     0.042     0.075
 Number   :     10027     10039     10039     10039      9912      9912      9912      9984      9984      9984

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.864    -0.061     0.305     0.499    -0.167     0.406     0.632    -0.295     0.600     0.352
 Shift    :     0.041    -0.006    -0.008    -0.074     0.000    -0.002     0.003    -0.033     0.003    -0.010
 New value:     0.904    -0.067     0.298     0.425    -0.167     0.404     0.635    -0.328     0.603     0.342
 Error    :     0.070     0.040     0.074     0.068     0.038     0.072     0.064     0.037     0.069     0.064
 Number   :     10187     10187     10187     10582     10582     10582     11235     11235     11235     11843

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.157     0.363     0.585     0.015     0.311     0.642     0.047     0.454     0.269     0.063
 Shift    :    -0.007    -0.003     0.002    -0.001    -0.015     0.024     0.025    -0.011    -0.137    -0.051
 New value:    -0.164     0.359     0.586     0.013     0.296     0.666     0.072     0.443     0.131     0.012
 Error    :     0.035     0.069     0.063     0.038     0.071     0.085     0.047     0.102     0.254     0.151
 Number   :     11843     11843     12037     12037     12037      8292      8292      8292      3418      3418

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:    -0.087     1.000     0.984     1.015     1.203     1.110     1.107     0.924     0.876     0.758
 Shift    :    -0.062     0.000     0.017     0.003     0.016     0.006     0.011     0.007     0.008     0.007
 New value:    -0.148     1.000     1.000     1.018     1.218     1.116     1.119     0.932     0.884     0.765
 Error    :     0.304     0.008     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3418      7045     11118     14199     14230     14142     14186     14150     14164     13997

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.586     0.641     0.558     0.549     0.515     0.503     0.493     0.464
 Shift    :     0.005     0.007     0.004     0.006     0.005     0.004     0.006     0.001
 New value:     0.590     0.648     0.562     0.555     0.520     0.507     0.499     0.465
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.008
 Number   :     14144     14361     15050     15860     16500     15664     10807      5878


  =====  Cycle     4  =====
 Residual Sum( w Del**2) =      0.159E+06, restraint residual =       0.00    , total residual =       0.458E+06
 Sum( w Del**2) / (m-n) =       2.407    
    2 eigenvalues filtered out, smallest =   0.994E-10, smallest filtered =    0.757E-07   Damping factor =   0.000
    66172 observations used from     3924 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              619    outliers


 Mean and maximum shift/sd :      0.293     1.050 (parameter    33   B1.11:3 )



=== Shifts for cycle    4


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.929    -0.462    -0.918     1.132    -0.527     0.734     1.160    -0.861     0.466     2.191
 Shift    :    -0.041     0.024     0.095    -0.051    -0.003    -0.004    -0.052     0.012    -0.033    -0.035
 New value:     0.888    -0.439    -0.823     1.081    -0.530     0.730     1.108    -0.849     0.433     2.156
 Error    :     0.113     0.066     0.123     0.084     0.049     0.088     0.087     0.048     0.084     0.091
 Number   :      4821      4821      4821      9036      9036      9036     10125     10125     10125      9954

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.051     0.483     2.563    -0.067     0.122     2.592    -0.152     0.438     2.532     0.078
 Shift    :     0.002    -0.035    -0.030    -0.012    -0.027    -0.045     0.003    -0.042    -0.032     0.003
 New value:     0.052     0.448     2.533    -0.080     0.095     2.547    -0.149     0.396     2.501     0.081
 Error    :     0.050     0.087     0.089     0.050     0.085     0.088     0.049     0.084     0.085     0.046
 Number   :      9954      9954      9967      9967      9967     10080     10080     10080     10027     10027

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.377     2.140    -0.656    -0.229     1.060    -0.661    -0.155     1.498    -0.073    -0.131
 Shift    :    -0.039    -0.033    -0.005    -0.050    -0.028     0.026    -0.017    -0.047     0.007    -0.030
 New value:     0.338     2.107    -0.662    -0.279     1.032    -0.635    -0.173     1.450    -0.067    -0.161
 Error    :     0.080     0.085     0.047     0.083     0.081     0.045     0.082     0.074     0.042     0.075
 Number   :     10027     10043     10043     10043      9909      9909      9909      9973      9973      9973

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.904    -0.067     0.298     0.425    -0.167     0.404     0.635    -0.328     0.603     0.342
 Shift    :    -0.026    -0.005    -0.077    -0.056    -0.003    -0.026    -0.028    -0.008    -0.029    -0.034
 New value:     0.878    -0.072     0.221     0.368    -0.170     0.379     0.606    -0.336     0.575     0.307
 Error    :     0.070     0.040     0.073     0.068     0.038     0.072     0.064     0.037     0.069     0.064
 Number   :     10172     10172     10172     10554     10554     10554     11193     11193     11193     11818

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.164     0.359     0.586     0.013     0.296     0.666     0.072     0.443     0.131     0.012
 Shift    :    -0.003    -0.019    -0.035     0.000    -0.033    -0.021     0.003    -0.048    -0.100    -0.002
 New value:    -0.167     0.340     0.552     0.013     0.263     0.645     0.075     0.395     0.031     0.010
 Error    :     0.035     0.069     0.063     0.038     0.071     0.085     0.047     0.102     0.253     0.151
 Number   :     11818     11818     12030     12030     12030      8294      8294      8294      3416      3416

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:    -0.148     1.000     1.000     1.018     1.218     1.116     1.119     0.932     0.884     0.765
 Shift    :    -0.002     0.000    -0.001    -0.001    -0.002    -0.001    -0.002    -0.001    -0.001     0.000
 New value:    -0.150     1.000     0.999     1.017     1.216     1.115     1.117     0.931     0.882     0.765
 Error    :     0.303     0.008     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3416      7021     11089     14177     14218     14142     14187     14154     14160     13993

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.590     0.648     0.562     0.555     0.520     0.507     0.499     0.465
 Shift    :    -0.001    -0.001    -0.001     0.000    -0.001    -0.001    -0.001    -0.001
 New value:     0.589     0.647     0.561     0.555     0.519     0.506     0.498     0.464
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.007
 Number   :     14139     14330     15014     15819     16478     15650     10806      5879


  =====  Cycle     5  =====
 Residual Sum( w Del**2) =      0.158E+06, restraint residual =       0.00    , total residual =       0.456E+06
 Sum( w Del**2) / (m-n) =       2.401    
    2 eigenvalues filtered out, smallest =  -0.140E-09, smallest filtered =    0.755E-07   Damping factor =   0.000
    66010 observations used from     3915 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              628    outliers


 Mean and maximum shift/sd :      0.180     0.496 (parameter     4   B1.2:1  )



=== Shifts for cycle    5


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.888    -0.439    -0.823     1.081    -0.530     0.730     1.108    -0.849     0.433     2.156
 Shift    :    -0.031     0.011     0.014    -0.042    -0.008     0.005    -0.028     0.002    -0.012    -0.031
 New value:     0.857    -0.427    -0.809     1.039    -0.537     0.735     1.080    -0.846     0.422     2.124
 Error    :     0.114     0.066     0.123     0.084     0.049     0.088     0.087     0.048     0.084     0.091
 Number   :      4795      4795      4795      9001      9001      9001     10098     10098     10098      9936

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.052     0.448     2.533    -0.080     0.095     2.547    -0.149     0.396     2.501     0.081
 Shift    :     0.002    -0.036    -0.031     0.000    -0.024    -0.031    -0.001    -0.030    -0.030     0.001
 New value:     0.055     0.412     2.503    -0.079     0.071     2.516    -0.150     0.366     2.470     0.082
 Error    :     0.051     0.087     0.089     0.050     0.085     0.088     0.049     0.084     0.085     0.046
 Number   :      9936      9936      9955      9955      9955     10072     10072     10072     10015     10015

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.338     2.107    -0.662    -0.279     1.032    -0.635    -0.173     1.450    -0.067    -0.161
 Shift    :    -0.020    -0.030    -0.005    -0.031    -0.033    -0.005    -0.027    -0.023     0.004    -0.027
 New value:     0.318     2.078    -0.666    -0.310     0.999    -0.640    -0.200     1.427    -0.063    -0.188
 Error    :     0.080     0.085     0.047     0.084     0.081     0.045     0.082     0.074     0.042     0.075
 Number   :     10015     10027     10027     10027      9891      9891      9891      9948      9948      9948

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.878    -0.072     0.221     0.368    -0.170     0.379     0.606    -0.336     0.575     0.307
 Shift    :    -0.032    -0.003    -0.016    -0.017    -0.003    -0.036    -0.024     0.001    -0.025    -0.027
 New value:     0.846    -0.074     0.204     0.351    -0.173     0.343     0.583    -0.335     0.550     0.280
 Error    :     0.070     0.040     0.074     0.068     0.038     0.072     0.064     0.037     0.069     0.064
 Number   :     10139     10139     10139     10519     10519     10519     11160     11160     11160     11783

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.167     0.340     0.552     0.013     0.263     0.645     0.075     0.395     0.031     0.010
 Shift    :    -0.002    -0.010    -0.027     0.000    -0.029    -0.028    -0.005    -0.035    -0.007     0.034
 New value:    -0.169     0.331     0.525     0.013     0.234     0.617     0.070     0.361     0.025     0.044
 Error    :     0.035     0.069     0.063     0.038     0.071     0.085     0.047     0.102     0.254     0.152
 Number   :     11783     11783     12000     12000     12000      8274      8274      8274      3406      3406

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:    -0.150     1.000     0.999     1.017     1.216     1.115     1.117     0.931     0.882     0.765
 Shift    :    -0.009     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 New value:    -0.160     1.000     0.999     1.017     1.216     1.115     1.117     0.931     0.882     0.765
 Error    :     0.304     0.008     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3406      6991     11048     14131     14194     14122     14174     14135     14140     13969

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.589     0.647     0.561     0.555     0.519     0.506     0.498     0.464
 Shift    :     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 New value:     0.589     0.647     0.561     0.555     0.519     0.506     0.498     0.465
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.007
 Number   :     14103     14291     14964     15770     16434     15605     10777      5864


  =====  Cycle     6  =====
 Residual Sum( w Del**2) =      0.158E+06, restraint residual =       0.00    , total residual =       0.456E+06
 Sum( w Del**2) / (m-n) =       2.399    
    2 eigenvalues filtered out, smallest =  -0.141E-09, smallest filtered =    0.753E-07   Damping factor =   0.000
    65992 observations used from     3914 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              629    outliers


 Mean and maximum shift/sd :      0.169     0.405 (parameter    34   B1.12:1 )



=== Shifts for cycle    6


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.857    -0.427    -0.809     1.039    -0.537     0.735     1.080    -0.846     0.422     2.124
 Shift    :    -0.035    -0.004     0.031    -0.020     0.000    -0.030    -0.029     0.001    -0.020    -0.021
 New value:     0.822    -0.431    -0.778     1.020    -0.537     0.705     1.051    -0.845     0.402     2.103
 Error    :     0.114     0.066     0.124     0.084     0.049     0.089     0.087     0.048     0.084     0.091
 Number   :      4794      4794      4794      8998      8998      8998     10096     10096     10096      9935

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.055     0.412     2.503    -0.079     0.071     2.516    -0.150     0.366     2.470     0.082
 Shift    :    -0.002    -0.025    -0.027     0.004    -0.024    -0.023    -0.001    -0.016    -0.024     0.001
 New value:     0.053     0.386     2.476    -0.076     0.047     2.493    -0.151     0.349     2.446     0.083
 Error    :     0.051     0.087     0.089     0.050     0.085     0.088     0.049     0.084     0.085     0.046
 Number   :      9935      9935      9953      9953      9953     10070     10070     10070     10013     10013

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.318     2.078    -0.666    -0.310     0.999    -0.640    -0.200     1.427    -0.063    -0.188
 Shift    :    -0.027    -0.024    -0.001    -0.020    -0.024     0.001    -0.028    -0.024     0.000    -0.025
 New value:     0.290     2.053    -0.667    -0.330     0.975    -0.639    -0.228     1.403    -0.063    -0.213
 Error    :     0.080     0.085     0.047     0.084     0.081     0.045     0.082     0.074     0.042     0.075
 Number   :     10013     10025     10025     10025      9891      9891      9891      9948      9948      9948

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.846    -0.074     0.204     0.351    -0.173     0.343     0.583    -0.335     0.550     0.280
 Shift    :    -0.022     0.000    -0.020    -0.028    -0.002    -0.028    -0.023     0.003    -0.025    -0.021
 New value:     0.824    -0.074     0.185     0.323    -0.175     0.315     0.560    -0.332     0.525     0.259
 Error    :     0.070     0.040     0.074     0.068     0.038     0.072     0.064     0.037     0.069     0.064
 Number   :     10133     10133     10133     10514     10514     10514     11154     11154     11154     11781

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.169     0.331     0.525     0.013     0.234     0.617     0.070     0.361     0.025     0.044
 Shift    :    -0.004    -0.013    -0.024     0.004    -0.027    -0.019    -0.006    -0.029    -0.035     0.012
 New value:    -0.173     0.318     0.501     0.017     0.207     0.598     0.064     0.332    -0.010     0.056
 Error    :     0.035     0.069     0.063     0.038     0.071     0.085     0.047     0.102     0.254     0.151
 Number   :     11781     11781     11993     11993     11993      8271      8271      8271      3403      3403

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:    -0.160     1.000     0.999     1.017     1.216     1.115     1.117     0.931     0.882     0.765
 Shift    :    -0.010     0.000     0.000    -0.001     0.000    -0.001     0.000    -0.001     0.000     0.000
 New value:    -0.170     1.000     0.999     1.016     1.216     1.115     1.116     0.931     0.882     0.764
 Error    :     0.304     0.008     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3403      6989     11046     14130     14191     14121     14170     14132     14138     13968

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.589     0.647     0.561     0.555     0.519     0.506     0.498     0.465
 Shift    :     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 New value:     0.589     0.647     0.561     0.554     0.519     0.506     0.498     0.464
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.007
 Number   :     14102     14285     14958     15762     16433     15598     10773      5860


  =====  Cycle     7  =====
 Residual Sum( w Del**2) =      0.158E+06, restraint residual =       0.00    , total residual =       0.456E+06
 Sum( w Del**2) / (m-n) =       2.399    
    2 eigenvalues filtered out, smallest =  -0.435E-09, smallest filtered =    0.753E-07   Damping factor =   0.000
    65975 observations used from     3913 independent reflections
 Whole reflections rejected (all observations):
             4175    too weak
              630    outliers


 Mean and maximum shift/sd :      0.089     0.210 (parameter    40   B1.14:1 )



=== Shifts for cycle    7


 Run number     1

 Parameter:    B1.1:1    B1.1:2    B1.1:3    B1.2:1    B1.2:2    B1.2:3    B1.3:1    B1.3:2    B1.3:3    B1.4:1  
 Old value:     0.822    -0.431    -0.778     1.020    -0.537     0.705     1.051    -0.845     0.402     2.103
 Shift    :    -0.007    -0.004    -0.011    -0.014     0.001    -0.014    -0.013     0.000    -0.014    -0.013
 New value:     0.816    -0.435    -0.789     1.005    -0.537     0.691     1.038    -0.845     0.388     2.090
 Error    :     0.114     0.066     0.124     0.084     0.049     0.089     0.087     0.048     0.084     0.091
 Number   :      4793      4793      4793      8997      8997      8997     10095     10095     10095      9933

 Parameter:    B1.4:2    B1.4:3    B1.5:1    B1.5:2    B1.5:3    B1.6:1    B1.6:2    B1.6:3    B1.7:1    B1.7:2  
 Old value:     0.053     0.386     2.476    -0.076     0.047     2.493    -0.151     0.349     2.446     0.083
 Shift    :     0.000    -0.014    -0.013     0.001    -0.016    -0.013     0.000    -0.013    -0.013     0.000
 New value:     0.053     0.373     2.463    -0.075     0.032     2.480    -0.152     0.337     2.433     0.083
 Error    :     0.051     0.087     0.089     0.050     0.085     0.088     0.049     0.084     0.085     0.046
 Number   :      9933      9933      9952      9952      9952     10070     10070     10070     10013     10013

 Parameter:    B1.7:3    B1.8:1    B1.8:2    B1.8:3    B1.9:1    B1.9:2    B1.9:3    B1.10:1   B1.10:2   B1.10:3 
 Old value:     0.290     2.053    -0.667    -0.330     0.975    -0.639    -0.228     1.403    -0.063    -0.213
 Shift    :    -0.014    -0.013     0.000    -0.013    -0.013     0.000    -0.014    -0.013     0.000    -0.014
 New value:     0.277     2.040    -0.667    -0.343     0.962    -0.639    -0.242     1.390    -0.063    -0.227
 Error    :     0.080     0.085     0.047     0.084     0.081     0.045     0.082     0.074     0.042     0.075
 Number   :     10013     10025     10025     10025      9890      9890      9890      9946      9946      9946

 Parameter:    B1.11:1   B1.11:2   B1.11:3   B1.12:1   B1.12:2   B1.12:3   B1.13:1   B1.13:2   B1.13:3   B1.14:1 
 Old value:     0.824    -0.074     0.185     0.323    -0.175     0.315     0.560    -0.332     0.525     0.259
 Shift    :    -0.013     0.000    -0.014    -0.013     0.000    -0.014    -0.013    -0.001    -0.013    -0.013
 New value:     0.811    -0.074     0.171     0.310    -0.175     0.301     0.546    -0.333     0.512     0.245
 Error    :     0.070     0.040     0.074     0.068     0.038     0.072     0.064     0.037     0.069     0.064
 Number   :     10132     10132     10132     10510     10510     10510     11148     11148     11148     11775

 Parameter:    B1.14:2   B1.14:3   B1.15:1   B1.15:2   B1.15:3   B1.16:1   B1.16:2   B1.16:3   B1.17:1   B1.17:2 
 Old value:    -0.173     0.318     0.501     0.017     0.207     0.598     0.064     0.332    -0.010     0.056
 Shift    :     0.000    -0.012    -0.013     0.000    -0.014    -0.014     0.000    -0.013    -0.015    -0.003
 New value:    -0.173     0.306     0.488     0.017     0.193     0.585     0.064     0.319    -0.026     0.053
 Error    :     0.035     0.069     0.063     0.038     0.071     0.085     0.047     0.102     0.254     0.152
 Number   :     11775     11775     11988     11988     11988      8265      8265      8265      3401      3401

 Parameter:    B1.17:3   K1.1.1    K1.2.1    K1.3.1    K1.4.1    K1.5.1    K1.6.1    K1.7.1    K1.8.1    K1.9.1  
 Old value:    -0.170     1.000     0.999     1.016     1.216     1.115     1.116     0.931     0.882     0.764
 Shift    :    -0.017     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 New value:    -0.187     1.000     0.998     1.016     1.216     1.114     1.116     0.931     0.882     0.764
 Error    :     0.304     0.008     0.008     0.008     0.011     0.009     0.010     0.007     0.007     0.006
 Number   :      3401      6988     11044     14127     14189     14119     14169     14132     14137     13967

 Parameter:    K1.10.1   K1.11.1   K1.12.1   K1.13.1   K1.14.1   K1.15.1   K1.16.1   K1.17.1 
 Old value:     0.589     0.647     0.561     0.554     0.519     0.506     0.498     0.464
 Shift    :     0.000     0.000     0.000     0.000     0.000     0.000     0.000     0.000
 New value:     0.589     0.647     0.560     0.554     0.519     0.506     0.498     0.464
 Error    :     0.004     0.005     0.004     0.004     0.004     0.004     0.006     0.007
 Number   :     14100     14281     14952     15756     16423     15589     10767      5856

Final scale factors

************************************************************************************************************************ Final scale factors: ==================== ============ Run 1 ============= Relative B-factors: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 B-smooth: 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 B-fac-yy: 0.8 1.0 1.0 2.1 2.5 2.5 2.4 2.0 1.0 1.4 0.8 0.3 0.5 0.2 0.5 sd-yy: 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 B-fac-yz: -0.4 -0.5 -0.8 0.1 -0.1 -0.2 0.1 -0.7 -0.6 -0.1 -0.1 -0.2 -0.3 -0.2 0.0 sd-yz: 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 B-fac-zz: -0.8 0.7 0.4 0.4 0.0 0.3 0.3 -0.3 -0.2 -0.2 0.2 0.3 0.5 0.3 0.2 sd-zz: 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Bfac_min: -0.9 0.3 -0.2 0.4 0.0 0.3 0.3 -0.5 -0.5 -0.2 0.2 0.1 0.2 0.1 0.2 Bfac_max: 0.9 1.4 1.6 2.1 2.5 2.5 2.4 2.2 1.2 1.4 0.8 0.5 0.9 0.5 0.5 Bfac_mean: 0.0 0.8 0.7 1.2 1.2 1.4 1.4 0.8 0.4 0.6 0.5 0.3 0.5 0.3 0.3 Bfac_rot: 75.8 53.2 55.5 -88.2 88.2 86.0 -87.8 75.4 66.6 87.8 83.5 45.8 46.5 40.0 -86.7 Position: 0.0 10.0 20.0 30.0 40.0 50.0 60.0 70.0 80.0 90.0 100.0 110.0 120.0 130.0 140.0 16 17 B-smooth: 0.0 0.0 B-fac-yy: 0.6 0.0 sd-yy: 0.1 0.3 B-fac-yz: 0.1 0.1 sd-yz: 0.0 0.2 B-fac-zz: 0.3 -0.2 sd-zz: 0.1 0.3 Bfac_min: 0.3 -0.2 Bfac_max: 0.6 0.0 Bfac_mean: 0.5 -0.1 Bfac_rot: -77.1 73.3 Position: 150.0 160.0 Scales -- smoothed, individual, (sd): 1 2 3 4 5 6 7 8 1.000 1.002 1.049 1.146 1.135 1.071 0.953 0.863 1.000 0.998 1.016 1.216 1.114 1.116 0.931 0.882 (0.008) (0.008) (0.008) (0.011) (0.009) (0.010) (0.007) (0.007) Rotation 0.00 10.00 20.00 30.00 40.00 50.00 60.00 70.00 9 10 11 12 13 14 15 16 0.738 0.632 0.614 0.575 0.548 0.523 0.507 0.492 0.764 0.589 0.647 0.560 0.554 0.519 0.506 0.498 (0.006) (0.004) (0.005) (0.004) (0.004) (0.004) (0.004) (0.006) Rotation 80.00 90.00 100.00 110.00 120.00 130.00 140.00 150.00 17 0.473 0.464 (0.007) Rotation 160.00 ================================================================================ ================================================================================ ================================================================================ ------ Analysis Pass ------ ================================================================================ ================================================================================ ================================================================================ Fully-recorded and summed partial reflections will be used in analysis Summed partials will be checked for consistent MPART flags sets with consistent MPART flags will be accepted sets with inconsistent MPART flags will be tested on the total fraction Summed partials must contain not more than 5 parts Summed partials accepted if total fraction lies between 0.950 and 1.050 Partials with missing parts in the middle will be accepted Outliers will be omitted from output file Reduced indices hkl will be output (ie reduced to asymmetric unit as in input file) Intensity bins, WILSON mode, mid-bin intensity = 1817. Outliers with two observations will be kept =========================== Normal probability analysis ====== Run number: 1, Fulls ====== Number Slope Intercept All data: 46678 1.529 -0.193 Data within expected delta 0.90: 29494 1.282 -0.150 ====== Run number: 1, Partials ====== Number Slope Intercept All data: 147960 1.630 0.081 Data within expected delta 0.90: 93492 1.312 0.066 Update of SDcorrection parameters: Fulls Partials initial values: 1.0000 0.0000 0.0200 1.0000 0.0000 0.0200 changed to: 1.2818 1.3124 ========================================== Average Intensities in 4(sin theta/lambda)**2 bins N 1/resol^2 Mn(I/Eps) 1 0.0076 3876. 2 0.0195 2354. 3 0.0322 2080. 4 0.0449 1660. 5 0.0577 1397. 6 0.0704 955. 7 0.0832 684. 8 0.0959 455. 9 0.1087 156. 10 0.1207 65. ================================================================================ ================================================================================ ================================================================================ ------ Final Pass for statistics of merging ------ ================================================================================ ================================================================================ ================================================================================ FORMATTED UNKNOWN file opened on unit 15 Logical name: ROGUES, Filename: ROGUES FORMATTED UNKNOWN file opened on unit 8 Logical name: NORMPLOT, Filename: NORMPLOT ******************************************************************************** ******************************************************************************** Statistics for all datasets (Q)QOPEN: file opened on unit 2 Status: UNKNOWN Logical Name: HKLOUT Filename: native_sars_scala_p6522.mtz HEADER INFORMATION FOR OUTPUT MTZ FILE ON INDEX 1 * Title: native SARS michael robertson's raxis II data.. * Number of Datasets = 1 * Dataset ID, project/crystal name, dataset name, cell dimensions, wavelength: 1 Unspecified / Unspecified 94.0378 94.0378 130.2772 90.0000 90.0000 120.0000 1.54180 * Number of Columns = 9 * Number of Reflections = 8750 * Missing value set to NaN in input mtz file * Missing value set to NaN in output mtz file * Column Labels : H K L IMEAN SIGIMEAN I(+) SIGI(+) I(-) SIGI(-) * Column Types : H H H J Q K M K M * Associated datasets : 1 1 1 1 1 1 1 1 1 * Cell Dimensions : 94.0378 94.0378 130.2772 90.0000 90.0000 120.0000 * Resolution Range : 0.00051 0.12780 ( 44.227 - 2.797 A ) * Sort Order : 1 2 3 4 5 * Space group = P6522 (number 179) Number of observations read : 266171 Number of unique reflections read : 8802 Number of observations output : 8750 Number of outliers rejected : 468 Number of observations rejected on Emax limit : 0 Number of observations outside resolution limits : 0 (observations outside resolution limits are omitted from the output file) Statistics below are accumulated from:- 8700 unique reflections, 147492 observations (of which 46550 are fully recorded, 100942 are summed partials, 0 are scaled partials) this excludes 50 good observations measured once only Maximum number of parts in a partially recorded reflection: 5 6 partial sets with too many parts 6216 partial sets with total fraction too small 58 partial sets with total fraction too large ================================================================================ Analysis of applied scale factors (including input scale) Mean scale factors analysed by Batch for each run and resolution Rotation 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 dmax 8.84 1.00 1.00 1.00 0.99 1.00 0.99 0.99 0.99 0.99 0.99 0.99 1.00 1.00 1.01 1.01 1.01 1.02 1.02 6.25 0.99 0.99 0.99 0.99 0.99 0.99 0.99 0.98 0.98 0.98 0.98 0.98 0.99 0.99 0.99 1.00 1.01 1.01 5.10 0.98 0.99 0.98 0.98 0.98 0.98 0.98 0.97 0.97 0.97 0.97 0.97 0.97 0.98 0.98 0.99 1.00 1.00 4.42 0.98 0.98 0.98 0.97 0.97 0.97 0.96 0.96 0.96 0.96 0.96 0.96 0.96 0.97 0.97 0.97 0.98 0.98 3.95 0.97 0.97 0.97 0.97 0.96 0.96 0.96 0.95 0.95 0.95 0.95 0.95 0.95 0.96 0.96 0.96 0.97 0.98 3.61 0.96 0.96 0.96 0.96 0.95 0.95 0.95 0.95 0.94 0.94 0.94 0.94 0.94 0.95 0.95 0.95 0.96 0.96 3.34 0.96 0.96 0.96 0.95 0.95 0.94 0.94 0.93 0.93 0.93 0.93 0.93 0.93 0.93 0.93 0.95 0.95 0.95 3.13 0.96 0.96 0.95 0.95 0.94 0.93 0.93 0.93 0.92 0.92 0.92 0.92 0.92 0.92 0.93 0.93 0.94 0.94 2.95 0.96 0.95 0.95 0.93 0.93 0.93 0.92 0.91 0.91 0.91 0.91 0.91 0.91 0.91 0.92 0.92 0.92 0.94 2.80 0.96 0.94 0.93 0.94 0.93 0.92 0.91 0.92 0.90 0.90 0.90 0.90 0.90 0.90 0.91 0.91 0.92 0.93 Overall 0.97 0.96 0.96 0.96 0.95 0.95 0.95 0.94 0.94 0.94 0.94 0.93 0.94 0.94 0.95 0.95 0.95 0.96 Rotation 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 dmax 8.84 1.03 1.04 1.04 1.05 1.06 1.07 1.09 1.09 1.10 1.11 1.12 1.13 1.13 1.14 1.14 1.13 1.13 1.13 6.25 1.02 1.02 1.03 1.04 1.05 1.06 1.07 1.07 1.09 1.09 1.10 1.10 1.11 1.11 1.11 1.11 1.11 1.11 5.10 1.00 1.01 1.02 1.02 1.03 1.04 1.05 1.06 1.06 1.07 1.08 1.09 1.09 1.09 1.09 1.09 1.08 1.08 4.42 0.99 1.00 1.00 1.01 1.02 1.03 1.03 1.04 1.05 1.05 1.06 1.06 1.07 1.07 1.06 1.06 1.06 1.06 3.95 0.98 0.98 0.99 1.00 1.00 1.01 1.01 1.02 1.03 1.03 1.03 1.04 1.04 1.05 1.03 1.04 1.04 1.04 3.61 0.97 0.98 0.98 0.98 0.99 1.00 1.00 1.00 1.01 1.01 1.01 1.02 1.01 1.02 1.02 1.02 1.01 1.01 3.34 0.96 0.96 0.96 0.97 0.97 0.98 0.98 0.99 0.99 1.00 1.00 1.00 0.99 1.00 0.99 0.99 0.99 0.99 3.13 0.94 0.95 0.95 0.96 0.96 0.97 0.97 0.97 0.97 0.98 0.98 0.98 0.98 0.98 0.98 0.97 0.97 0.97 2.95 0.93 0.94 0.95 0.95 0.95 0.95 0.96 0.96 0.96 0.96 0.96 0.96 0.96 0.96 0.96 0.95 0.95 0.95 2.80 0.93 0.93 0.94 0.94 0.94 0.94 0.94 0.94 0.95 0.95 0.94 0.94 0.94 0.95 0.93 0.94 0.93 0.94 Overall 0.97 0.97 0.98 0.98 0.99 0.99 1.00 1.00 1.00 1.01 1.01 1.02 1.01 1.02 1.01 1.01 1.01 1.01 Rotation 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 dmax 8.84 1.13 1.13 1.12 1.12 1.11 1.11 1.11 1.10 1.09 1.09 1.08 1.07 1.06 1.06 1.05 1.04 1.03 1.01 6.25 1.10 1.10 1.10 1.09 1.09 1.09 1.08 1.07 1.07 1.07 1.06 1.04 1.04 1.03 1.02 1.01 1.00 0.99 5.10 1.07 1.08 1.07 1.07 1.07 1.05 1.05 1.04 1.04 1.04 1.03 1.02 1.01 1.00 1.00 0.99 0.98 0.97 4.42 1.06 1.05 1.05 1.05 1.04 1.03 1.03 1.02 1.02 1.02 1.00 0.99 0.99 0.98 0.97 0.97 0.96 0.94 3.95 1.03 1.03 1.03 1.02 1.02 1.01 1.01 1.00 1.00 0.98 0.98 0.97 0.97 0.96 0.95 0.94 0.93 0.91 3.61 1.01 1.00 1.00 1.00 0.99 0.98 0.99 0.98 0.96 0.97 0.96 0.95 0.94 0.93 0.93 0.92 0.91 0.89 3.34 0.99 0.98 0.98 0.98 0.97 0.97 0.96 0.95 0.94 0.95 0.93 0.93 0.91 0.92 0.91 0.90 0.89 0.87 3.13 0.96 0.95 0.96 0.95 0.94 0.95 0.92 0.94 0.93 0.91 0.91 0.91 0.90 0.89 0.88 0.88 0.86 0.85 2.95 0.94 0.95 0.94 0.94 0.92 0.92 0.92 0.91 0.90 0.91 0.89 0.88 0.87 0.88 0.87 0.86 0.84 0.83 2.80 0.93 0.91 0.93 0.92 0.92 0.91 0.90 0.89 0.90 0.87 0.88 0.88 0.87 0.84 0.84 0.84 0.83 0.83 Overall 1.00 1.00 1.00 0.99 0.99 0.98 0.98 0.97 0.96 0.96 0.95 0.94 0.94 0.93 0.92 0.92 0.91 0.89 Rotation 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 dmax 8.84 1.00 0.99 0.97 0.96 0.95 0.94 0.93 0.92 0.92 0.90 0.89 0.89 0.88 0.87 0.86 0.86 0.85 0.84 6.25 0.97 0.97 0.95 0.94 0.93 0.92 0.91 0.91 0.90 0.89 0.88 0.87 0.86 0.85 0.85 0.84 0.83 0.83 5.10 0.95 0.94 0.93 0.92 0.91 0.90 0.89 0.89 0.88 0.87 0.86 0.85 0.85 0.84 0.83 0.83 0.82 0.81 4.42 0.93 0.92 0.91 0.90 0.88 0.87 0.87 0.86 0.86 0.85 0.84 0.84 0.83 0.82 0.82 0.81 0.81 0.79 3.95 0.90 0.90 0.89 0.88 0.87 0.86 0.85 0.84 0.84 0.84 0.82 0.81 0.81 0.81 0.80 0.80 0.80 0.79 3.61 0.89 0.88 0.86 0.85 0.84 0.84 0.83 0.82 0.81 0.81 0.81 0.80 0.79 0.79 0.79 0.78 0.78 0.78 3.34 0.86 0.85 0.85 0.84 0.82 0.81 0.81 0.81 0.81 0.79 0.79 0.78 0.79 0.78 0.77 0.77 0.77 0.76 3.13 0.85 0.83 0.82 0.81 0.81 0.81 0.80 0.78 0.78 0.78 0.78 0.77 0.77 0.76 0.77 0.76 0.76 0.75 2.95 0.82 0.82 0.81 0.80 0.79 0.78 0.77 0.78 0.77 0.76 0.76 0.75 0.76 0.74 0.75 0.74 0.75 0.75 2.80 0.81 0.80 0.80 0.78 0.77 0.77 0.76 0.76 0.76 0.75 0.75 0.75 0.74 0.74 0.73 0.75 0.74 0.73 Overall 0.88 0.87 0.86 0.85 0.84 0.83 0.83 0.82 0.82 0.81 0.80 0.80 0.80 0.79 0.78 0.78 0.78 0.77 Rotation 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 dmax 8.84 0.83 0.81 0.80 0.79 0.78 0.76 0.75 0.74 0.73 0.71 0.70 0.69 0.68 0.66 0.65 0.64 0.63 0.63 6.25 0.82 0.80 0.79 0.78 0.77 0.76 0.74 0.73 0.72 0.71 0.69 0.68 0.67 0.66 0.65 0.63 0.63 0.62 5.10 0.80 0.80 0.78 0.77 0.76 0.75 0.74 0.73 0.71 0.70 0.69 0.68 0.66 0.65 0.64 0.63 0.62 0.61 4.42 0.80 0.79 0.77 0.77 0.76 0.74 0.73 0.72 0.71 0.69 0.68 0.67 0.66 0.64 0.63 0.62 0.61 0.61 3.95 0.78 0.77 0.76 0.76 0.74 0.74 0.72 0.71 0.70 0.69 0.68 0.66 0.65 0.64 0.63 0.62 0.60 0.60 3.61 0.77 0.76 0.75 0.75 0.73 0.73 0.71 0.71 0.69 0.68 0.67 0.66 0.64 0.63 0.62 0.61 0.60 0.60 3.34 0.76 0.75 0.74 0.75 0.72 0.72 0.71 0.70 0.69 0.67 0.67 0.65 0.63 0.63 0.61 0.60 0.59 0.59 3.13 0.76 0.74 0.73 0.73 0.72 0.71 0.70 0.69 0.69 0.67 0.66 0.64 0.63 0.62 0.61 0.59 0.59 0.58 2.95 0.73 0.74 0.72 0.72 0.72 0.71 0.70 0.69 0.67 0.66 0.66 0.63 0.63 0.61 0.61 0.59 0.58 0.57 2.80 0.73 0.72 0.73 0.72 0.70 0.70 0.70 0.68 0.68 0.66 0.66 0.63 0.62 0.60 0.60 0.58 0.58 0.57 Overall 0.77 0.76 0.75 0.75 0.73 0.73 0.71 0.70 0.69 0.68 0.67 0.65 0.64 0.63 0.62 0.60 0.60 0.59 Rotation 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 dmax 8.84 0.63 0.62 0.62 0.62 0.62 0.61 0.61 0.61 0.61 0.61 0.61 0.61 0.60 0.60 0.60 0.59 0.59 0.58 6.25 0.62 0.62 0.61 0.61 0.61 0.61 0.61 0.61 0.61 0.61 0.61 0.60 0.60 0.60 0.59 0.59 0.58 0.58 5.10 0.61 0.61 0.61 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.59 0.59 0.59 0.58 0.58 4.42 0.60 0.60 0.60 0.60 0.60 0.60 0.60 0.59 0.60 0.60 0.59 0.59 0.59 0.59 0.58 0.58 0.58 0.57 3.95 0.60 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.59 0.58 0.58 0.58 0.57 0.57 3.61 0.59 0.59 0.58 0.59 0.58 0.59 0.58 0.59 0.58 0.59 0.59 0.58 0.58 0.58 0.58 0.57 0.57 0.57 3.34 0.59 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.57 0.57 0.57 0.56 3.13 0.58 0.58 0.57 0.57 0.57 0.57 0.58 0.57 0.58 0.58 0.58 0.58 0.57 0.57 0.57 0.57 0.56 0.56 2.95 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.57 0.56 0.56 0.56 2.80 0.57 0.56 0.56 0.56 0.56 0.56 0.57 0.56 0.57 0.57 0.57 0.57 0.57 0.57 0.56 0.56 0.56 0.56 Overall 0.59 0.59 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.58 0.57 0.57 0.57 Rotation 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 dmax 8.84 0.58 0.57 0.57 0.57 0.57 0.56 0.56 0.56 0.55 0.55 0.55 0.55 0.54 0.54 0.54 0.54 0.53 0.53 6.25 0.58 0.57 0.57 0.57 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.54 0.54 0.53 0.53 0.53 5.10 0.57 0.57 0.57 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.54 0.53 0.53 0.53 0.53 0.53 4.42 0.57 0.57 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.54 0.53 0.53 0.53 0.53 0.53 0.52 3.95 0.57 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.53 0.53 0.53 0.53 0.53 0.53 0.52 0.52 0.52 3.61 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.53 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.52 3.34 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.52 0.52 0.52 3.13 0.56 0.56 0.55 0.55 0.54 0.54 0.54 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.52 0.52 0.51 0.51 2.95 0.56 0.55 0.55 0.55 0.54 0.54 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 2.80 0.55 0.55 0.55 0.54 0.54 0.54 0.53 0.53 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.51 Overall 0.56 0.56 0.56 0.55 0.55 0.55 0.54 0.54 0.54 0.53 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.52 Rotation 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 dmax 8.84 0.53 0.53 0.53 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 6.25 0.53 0.52 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.50 5.10 0.52 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.49 4.42 0.52 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.49 0.49 3.95 0.52 0.52 0.52 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 3.61 0.52 0.51 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 0.49 3.34 0.51 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 0.49 0.48 3.13 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 0.48 0.48 0.48 2.95 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.48 0.48 0.48 0.48 0.48 2.80 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.48 0.48 0.48 0.48 0.48 0.48 Overall 0.52 0.51 0.51 0.51 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 0.49 Rotation 145 146 147 148 149 150 151 152 153 154 155 dmax 8.84 0.50 0.50 0.50 0.49 0.49 0.49 0.49 0.49 0.49 0.48 0.48 6.25 0.50 0.49 0.49 0.49 0.49 0.49 0.49 0.48 0.48 0.48 0.48 5.10 0.49 0.49 0.49 0.49 0.49 0.48 0.48 0.48 0.48 0.48 0.48 4.42 0.49 0.49 0.49 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 3.95 0.49 0.49 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.48 3.61 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.47 0.47 0.47 0.47 3.34 0.48 0.48 0.48 0.48 0.47 0.47 0.47 0.47 0.47 0.47 0.47 3.13 0.48 0.48 0.48 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 2.95 0.48 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 2.80 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 0.47 Overall 0.48 0.48 0.48 0.48 0.48 0.48 0.48 0.47 0.47 0.47 0.47

Scale factors by batch

Scale factors analysed by Batch for each run ============================================ Note that 0k below is calculated for the centre of each rotation range, at theta = 0 (for the B-factor) and at the centre of the detector: This will be inappropriate if the detector is not centred on the beam, and the scale varies across the detector Mn(k) is average applied scale, including any input scale 0k is the scale calculated from this scaling run For inline graphs use a Java browser Total 0.713 0.7384 0.7965 147542 468 Bfactor Mn(k) 0k Number NumReject

Agreement by batch

Agreement between batches ------------------------- RMS scatters are shown as SIGMA and SIGM0 for differences from Mn(I+),Mn(I-) and Mn(Imean) respectively. RFACTORS in this table are the differences from Mn(Imean), but in later tables RFACTORS are differences from Mn(I+),Mn(I-). NFR,NPR count those (mixed & unmixed sets) included in SIGMA NR those in SIGM0 and RFACTOR (mixed & unmixed FULLY/PARTIAL SETS) NBREJ number of reflections rejected for bad agreement NBRJM number of reflections rejected for M .gt. 1 (neither valid fully nor partial) For inline graphs use a Java browser Overall 1017.4 117.6 46550 100942 117.6 8.65 0.075 147492 468 0 0.003 Mn(Imean) SIGMA NFR NPR SIGM0 Imean/SIGM0 Rfactor NR NBREJ NBRJM FracRejtd ================================================================================ Rmerge against resolution for each run (deviation from mean I+ or I-) For inline graphs use a Java browser Overall 0.075 0.075 Run1 AllRun Rcum :- R-factor up to this range, Ranom :- Sum |Mn(I+) - Mn(I-)| / Sum (Mn(I+) + Mn(I-)) Rfull :- R-factor for fulls only, Nref :- number of independent hkl's SIGMA :- rms scatter of observations sd :- average standard deviation derived from experimental SDs, after :- application of SDFAC SDADD FRCBIAS :- Mean( Mn(If) - Ip )/Mean( Mn(I) ) for Nbias mixed sets only (If is a full if present, else the partial with the smallest number of parts)

Agreement by resolution

By 4SINTH/LASQ bins (all statistics relative to Mn(I)) ______________________________________________________________ For inline graphs use a Java browser Overall: 0.075 0.065 0.075 0.000 0 1017. 117.6 8.7 91. 39.1 147492 8700 1860 -0.033 97046 Rfac Rfull Rcum Ranom Nanom Av_I SIGMA I/sigma sd Mn(I)/sd Nmeas Nref Ncent FRCBIAS Nbias

Agreement by intensity

BY INTENSITY ranges (all statistics relative to Mn(I)) ______________________________________________________________ For inline graphs use a Java browser Overall 0.075 0.065 0.000 0 1017. 117.6 8.7 91.2 147492 8700 1860 -0.033 97046 -33.2 Rfac Rfull Ranom Nanom Av_I SIGMA I/Sigma sd Nmeas Nref Ncent FRCBIAS Nbias Abs.BIAS In the following analyses, Chi = (Ihl - Mn(Iothers) )/sqrt[sd(Ihl)**2 + sd(Mn(I))**2] Chi**2 analysis by position of detector (Xdet, Ydet) Each entry is 10 * Chi**2 (ie relative discrepancy **2) Xdet 95 190 285 380 475 570 665 760 855 950 1045 1140 1235 1330 1425 1520 1615 1710 1805 Ydet 95 0 0 0 0 0 0 0 6 5 6 6 7 0 0 0 0 0 0 0 0 190 0 0 0 0 1 5 7 7 8 8 7 7 7 7 0 0 0 0 0 0 285 0 0 0 5 5 6 7 9 13 13 10 11 7 6 7 7 0 0 0 0 380 0 0 6 6 8 8 11 13 15 15 14 12 10 8 7 6 7 0 0 0 475 0 0 6 7 10 10 13 15 12 13 10 12 14 10 9 7 6 0 0 0 570 0 7 6 10 13 13 13 13 9 11 10 12 22 18 13 9 6 8 0 0 665 0 8 9 13 12 9 24 21 13 11 13 25 37 32 14 12 8 6 0 0 760 19 10 15 16 12 10 23 15 12 11 11 21 37 42 31 17 14 7 2 0 855 9 14 40 21 17 10 13 14 11 15 12 16 25 37 29 22 38 14 13 0 950 0 178 135 113 46 22 17 14 19 73 22 13 18 19 29 69 49 87 0 0 1045 6 23 35 21 14 13 17 13 13 27 12 15 17 14 12 21 33 13 7 0 1140 9 9 12 14 16 13 15 12 11 11 9 12 16 11 10 15 10 8 3 0 1235 0 8 9 14 20 22 20 18 17 19 17 15 17 15 16 17 8 8 0 0 1330 0 6 8 13 22 33 23 18 23 19 15 15 15 22 21 15 8 11 0 0 1425 0 0 6 9 19 22 20 16 16 11 10 12 15 19 17 10 6 0 0 0 1520 0 0 4 6 9 14 12 11 11 10 11 11 12 14 9 7 6 0 0 0 1615 0 0 0 5 6 8 7 10 9 9 8 8 8 7 6 4 0 0 0 0 1710 0 0 0 0 4 6 7 7 7 7 7 7 7 6 8 0 0 0 0 0 1805 0 0 0 0 0 0 5 7 6 6 6 7 5 0 0 0 0 0 0 0 1900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Chi analysis by position of detector (Xdet, Ydet) Each entry is 10 * Mn(Chi) (ie signed relative discrepancy) Xdet 95 190 285 380 475 570 665 760 855 950 1045 1140 1235 1330 1425 1520 1615 1710 1805 Ydet 95 0 0 0 0 0 0 0 -1 -1 -1 0 -1 0 0 0 0 0 0 0 0 190 0 0 0 0 -4 0 -1 -1 -2 -3 -2 0 0 1 0 0 0 0 0 0 285 0 0 0 0 0 1 -1 -3 -4 -4 -2 -2 -1 1 1 2 0 0 0 0 380 0 0 0 1 1 1 -2 -4 -5 -5 -3 -2 -1 2 1 1 -3 0 0 0 475 0 0 0 2 3 2 -2 -4 -4 -4 -2 -2 -1 1 3 2 1 0 0 0 570 0 1 1 3 5 4 -1 -4 0 -1 0 -2 -3 1 2 3 1 0 0 0 665 0 0 0 0 1 2 -7 -5 -2 0 -2 -7 -9 -4 -3 0 0 0 0 0 760 -7 -3 -4 -2 -2 1 -7 -5 -4 -3 -3 -7 -12 -8 -8 -4 -5 -2 -5 0 855 -4 -5 -14 -7 -6 0 -1 -2 -5 -3 -3 -4 -5 -8 -11 -10 -13 -5 0 0 950 0 -42 -32 -28 -16 -8 -1 -1 -3 -1 2 3 0 -3 -10 -22 -18 -27 0 0 1045 0 -6 -13 -6 -2 5 4 3 1 5 3 6 6 3 -1 -6 -10 -6 -2 0 1140 5 -2 -4 -1 2 4 1 3 3 4 2 2 0 5 2 0 0 0 6 0 1235 0 1 0 4 7 10 2 2 5 7 5 1 -1 6 6 4 2 1 0 0 1330 0 1 2 6 8 12 9 8 9 8 6 6 5 10 8 6 3 3 0 0 1425 0 0 1 4 7 8 7 6 6 3 2 3 4 7 7 4 1 0 0 0 1520 0 0 1 2 4 6 4 3 2 0 0 2 3 5 4 2 3 0 0 0 1615 0 0 0 2 2 2 1 1 1 -1 0 0 1 2 2 0 0 0 0 0 1710 0 0 0 0 5 1 0 0 0 -1 -1 0 0 0 5 0 0 0 0 0 1805 0 0 0 0 0 0 -1 0 0 0 0 -1 4 0 0 0 0 0 0 0 1900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Number of observations in each area Xdet 95 190 285 380 475 570 665 760 855 950 1045 1140 1235 1330 1425 1520 1615 1710 1805 Ydet 95 0 0 0 0 0 0 0 117 328 887 321 114 0 0 0 0 0 0 0 0 190 0 0 0 0 1 240 623 851 885 1807 912 884 679 230 0 0 0 0 0 0 285 0 0 0 20 447 755 854 897 939 1936 947 924 884 829 482 29 0 0 0 0 380 0 0 13 468 696 796 845 908 929 1886 924 907 866 808 754 488 12 0 0 0 475 0 0 293 617 700 743 799 830 862 1769 868 829 790 756 690 647 291 0 0 0 570 0 74 490 568 616 665 719 744 776 1545 764 741 700 657 601 563 495 62 0 0 665 0 220 402 461 512 547 579 618 643 1298 636 603 574 523 495 459 412 204 0 0 760 3 242 319 342 379 420 445 461 470 953 470 463 430 386 366 340 314 251 1 0 855 20 148 180 206 236 260 281 286 257 494 255 277 274 237 226 216 175 138 15 0 950 0 2 7 41 79 106 138 139 101 144 98 131 129 102 76 32 6 4 0 0 1045 16 127 160 192 219 240 260 259 232 441 224 268 258 234 214 189 156 117 13 0 1140 2 251 304 326 362 400 419 449 443 904 458 440 428 387 361 324 281 238 2 0 1235 0 241 410 454 483 534 572 603 621 1247 623 596 584 531 484 447 397 204 0 0 1330 0 103 493 550 600 642 694 729 748 1522 744 731 684 642 587 537 463 88 0 0 1425 0 0 373 629 679 723 775 828 840 1735 843 810 769 739 697 621 339 0 0 0 1520 0 0 27 543 733 798 846 866 899 1847 905 877 846 794 732 541 17 0 0 0 1615 0 0 0 61 577 800 851 892 913 1853 921 909 855 813 551 40 0 0 0 0 1710 0 0 0 0 9 360 800 908 937 1887 935 900 766 336 7 0 0 0 0 0 1805 0 0 0 0 0 0 18 251 462 1169 460 238 13 0 0 0 0 0 0 0 1900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Completeness & multiplicity

Completeness and multiplicity, including reflections measured only once ======================================================================= %poss is completeness in the shell, Cm%poss in cumulative to that resolution The anomalous completeness values (AnomCmpl) are the percentage of acentrics measured AnomFrc is the % of measured acentric reflections for which an anomalous difference has been measured Rmeas: redundancy-independent (multiplicity-weighted) Rmerge or R(r.i.m.) (Rmeas is relative to I+ or I-, Rmeas0 is relative to overall mean) PCV: pooled coefficient of variation (PCV is relative to I+ or I-, PCV0 is relative to overall mean) PCV is a multiplicity-weighted RMS Rfactor See:- "Improved R-factors for diffraction data analysis in macromolecular crystallography" Kay Diederichs & P. Andrew Karplus, Nature Structural Biology, 4, 269-275 (1997) "On the use of the merging R factor as a qualityindicator for X-ray data" Manfred Weiss & Rolf Hilgenfeld, J.Appl.Cryst. 30, 203-205 (1997) "Global Indicators of X-ray data quality" Manfred Weiss, J.Appl.Cryst. 34, 130-135 (2001) For inline graphs use a Java browser Overall 147542 8750 1871 97.7 97.7 16.9 0.0 0.0 0.077 0.077 0.075 0.096 0.096 Nmeas Nref Ncent %poss Cm%poss Mlplcty AnomCmpl AnomFrc Rmeas Rmeas0 (Rsym) PCV PCV0

Axial reflections

For inline graphs use a Java browser For inline graphs use a Java browser

Analysis of standard deviations

ANALYSIS OF STANDARD DEVIATIONS =============================== This plots the distribution of the number of observations with Chi = (Ihl - Mn(Iothers) )/sqrt[sd(Ihl)**2 + sd(Mn(I))**2] in ranges from -5 to +5 . If the SD is a true estimate of the error, this distribution should have Mean=0.0 and Sigma=1.0 for all ranges of intensity. The analysis is repeated for ranges of increasing Imean. The Mean is expected to increase with Imean since the latter is a weighted mean and sd(Ihl) & Ihl are correlated. If the Sigma increases with Imean, increase the value of SdAdd. Current values of SD corrections are:-SdFac * Sqrt[sd(I)**2 + SdB I + (SdAdd I)**2] Fulls Partials Run SdFac SdB SdAdd SdFac SdB SdAdd 1 1.28176 0.00000 0.02000 1.31238 0.00000 0.02000 For inline graphs use a Java browser TOTALS: 0 -119. 28565. 1998. 46550 -0.13 1.11 1987. 100942 0.13 1.12 Range Imin Imax Irms Number MeanFull SigmaFull Irms Number MeanPart SigmaPartial Fully_recordeds Partially_recordeds For all REFLECTIONS, histogram of mean fractional deviations: FULLYS first and then PARTIALS DEL(I)/SD NUMBER in bin with upper limit DEL(I)/SD as shown -5.0 % -4.5 0 85 -4.0 0 70 -3.5 0 141 -3.0 1 265 * -2.5 1 498 ** -2.0 2 1097 ***** -1.5 5 2279 *********** -1.0 9 4306 ********************* -0.5 15 7165 *********************************** 0.0 20 9357 ********************************************** 0.5 19 8867 ******************************************** 1.0 13 6215 ****************************** 1.5 7 3419 ***************** 2.0 3 1562 ******* 2.5 1 674 *** 3.0 1 314 * 3.5 0 122 4.0 0 70 4.5 0 18 5.0 0 14 5.5 0 12 -5.0 % -4.5 0 146 -4.0 0 117 -3.5 0 187 -3.0 0 336 * -2.5 1 612 *** -2.0 1 1455 ******* -1.5 3 3176 *************** -1.0 7 7118 *********************************** -0.5 13 13183 ***************************************************************** 0.0 19 18845 ********************************************************************************************* 0.5 20 20178 **************************************************************************************************** 1.0 16 16015 ******************************************************************************* 1.5 10 9875 ************************************************* 2.0 5 5329 ************************** 2.5 2 2355 *********** 3.0 1 1112 ***** 3.5 0 474 ** 4.0 0 210 * 4.5 0 104 5.0 0 50 5.5 0 65 Analysis of total fraction for partials: 1) rejected (unmatched) partials 2) accepted partials with consistent MPART flags 3) accepted partials with inconsistent MPART flags Partiality N1 N2 N3 0.00 0.05 1357 0 0 0.05 0.10 194 1 0 0.10 0.15 191 1 0 0.15 0.20 136 3 0 0.20 0.25 133 4 0 0.25 0.30 139 1 0 0.30 0.35 116 11 0 0.35 0.40 104 4 0 0.40 0.45 99 4 0 0.45 0.50 102 7 0 0.50 0.55 116 5 0 0.55 0.60 153 9 0 0.60 0.65 201 5 0 0.65 0.70 245 4 0 0.70 0.71 55 0 0 0.71 0.72 59 0 0 0.72 0.73 58 1 0 0.73 0.74 49 0 0 0.74 0.75 73 1 0 0.75 0.76 69 4 0 0.76 0.77 84 4 0 0.77 0.78 71 1 0 0.78 0.79 83 5 0 0.79 0.80 79 3 0 0.80 0.81 94 11 0 0.81 0.82 96 29 0 0.82 0.83 108 26 0 0.83 0.84 94 17 0 0.84 0.85 126 25 0 0.85 0.86 105 19 0 0.86 0.87 135 40 0 0.87 0.88 154 26 0 0.88 0.89 153 24 0 0.89 0.90 158 25 0 0.90 0.91 172 30 0 0.91 0.92 177 35 0 0.92 0.93 218 62 0 0.93 0.94 198 90 0 0.94 0.95 262 188 0 0.95 0.96 0 631 312 0.96 0.97 0 1305 353 0.97 0.98 0 3904 504 0.98 0.99 0 10415 643 0.99 1.00 0 25868 2242 1.00 1.01 0 33921 337 1.01 1.02 0 10936 177 1.02 1.03 0 5317 95 1.03 1.04 2 1771 37 1.04 1.05 0 558 23 1.05 1.06 9 312 0 1.06 1.07 2 112 0 1.07 1.08 0 93 0 1.08 1.09 2 45 0 1.09 1.10 1 25 0 1.10 1.11 1 35 0 1.11 1.12 3 42 0 1.12 1.13 0 30 0 1.13 1.14 2 20 0 1.14 1.15 3 24 0 1.15 1.16 2 26 0 1.16 1.17 2 18 0 1.17 1.18 1 8 0 1.18 1.19 2 3 0 1.19 1.20 2 11 0 1.20 1.25 6 19 0 1.25 1.30 4 6 0 1.30 1.35 1 5 0 1.35 1.40 19 61 0 Histogram of number of parts in accepted summed partials 1 2 3 4 5 3290 87602 7702 1757 618 ================================================ Normal probability analysis, by run & partiality ====== Run number: 1, fulls ====== Number Slope Intercept All data: 46678 1.175 -0.141 Data within expected delta 0.90: 29494 0.987 -0.110 ====== Run number: 1, summed partials ====== Number Slope Intercept All data: 101282 1.248 0.166 Data within expected delta 0.90: 63998 0.995 0.133 ====== Run number: 1, fulls against fulls only ====== Number Slope Intercept All data: 46159 1.158 0.005 Data within expected delta 0.90: 29167 0.981 0.013 ========================================== Final assessment of SDcorrection multipliers Run Fulls Partials SdFac_used _corrected _fullsonly SdFac_used _corrected 1 1.2818 1.2657 1.2572 1.3124 1.3056 Harvest: Cant mkdir HARVESTHOME/DepositFiles/Unspecified - no deposit file created Scala: ** Normal termination ** Times: User: 39.5s System: 1.1s Elapsed: 0:41