Website Link | Reference | Journal Link | PMID | Local Copy | PDB |
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A Very Fast Minimal Hammerhead RNASara M. O'Rourke, William Estell and William G. ScottMinimal Hammerhead Ribozymes with Uncompromised Catalytic Activity. Journal of Molecular Biology 427: 2340–2347 (2015). 10.1016/j.jmb.2015.05.005 |
Paper
Supplemental Animation |
25981451 |
N/A |
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G-Quadruplex RNA StructuresAlastair C. Fyfe, Pete W. Dunten, Monika M. Martick and William G. ScottStructural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr2+ Ions. Journal of Molecular Biology 427: 2205-2219 (2015). |
Paper
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25861762 |
4RKV 4RJ1 4RNE |
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The Case for 2',3'-Cyclic PhosphatesWilliam G. Scott, Abraham Szöke, Josh Blaustein, Sara M. O'Rourke and Michael P. RobertsonRNA Catalysis, Thermodynamics and the Origin of Life. Life 4: 131-141 (2014). doi:10.3390/life4020131 |
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25370189 |
N/A |
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General or Specific Acid-Base Catalysis?Eric P. Schultz, E. Vazquez, and William G. ScottStructural and catalytic effects of an invariant purine substitution in the hammerhead ribozyme: implications for the mechanism of acid - base catalysis. Acta Crystallographica Section D: Biological Crystallography D70: 2256-2263 (2014). |
Paper
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25195740 |
3ZD4 3ZD5 |
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The Highest-Resolution Ribozyme StructureMichael Anderson, Eric P. Schultz, Monika Martick and William G. ScottActive-Site Monovalent Cations Revealed in a 1.55 Å Resolution Hammerhead Ribozyme Structure. Journal of Molecular Biology 425: 3790–3798 (2013). |
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23711504 |
3ZP8 |
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Do We Really Need Heavy Atom Derivatives?Michael P. Robertson, Young-In Chi and William G. ScottSolving novel RNA structures using only secondary structural fragments. Methods. (2010) Jun 9. |
Paper
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20541014 |
N/A |
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COOTEmsley P, Lohkamp B, Scott WG, Cowtan K.Features and development of Coot. Acta Crystallogr D66:486-501 (2010). |
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20383002 |
N/A |
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Antibody Interactions with HIV gp41 VariantsSara M. O'Rourke, Becky Schweighardt, William G. Scott, Terri Wrin, Dora P. A. J. Fonseca, Faruk Sinangil, and Phillip W. BermanRing Structure in the gp41 Trimer of Human Immunodeficiency Virus Type 1 That Modulates Sensitivity and Resistance to Broadly Neutralizing Antibodies. Journal of Virology83: 7728-7738 (2009). |
Paper
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19474108 |
N/A |
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Class III Hammerhead Ribozyme StructuresYoung-In Chi, Monika Martick, Rosalind Kim, William G. Scott and Sung-Hou KimCapturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis. PLoS Biology 6(9): e234 (2008). doi:10.1371/journal.pbio.0060234 |
Paper Accompanying commentary |
18834200 | 2QUS
(uncleaved) 2QUW (cleaved) |
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3'-UTR-embedded Hammerhead RNAs that Regulate Gene Expression in MammalsMonika Martick, Lucas H. Horan, Harry F. Noller & William G. ScottA discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA Nature 454: 899-902 (2008). |
Paper UCSC Press Release Supplemental |
18615019 | N/A | ||
A Glimpse of Biology's First EnzymeMichael P. Robertson and William G. ScottThe Structural Basis of Ribozyme-Catalyzed RNA Assembly Science 315: 1549-1553 (2007). |
Paper Perspective Supplemental |
17363667 | 2OIU | ||
The Full-Length Catalytically Active Hammerhead RNA StructureMonika Martick and William G. ScottTertiary Contacts Distant from the Active Site Prime a Ribozyme for Catalysis Cell 126: 309-320 (2006). |
Paper Commentary Supplemental |
16859740 | 2GOZ | ||
RNase EAnastasia J. Callaghan, Maria Jose Marcaida, Jonathan A. Stead, Kenneth J. McDowall, William G. Scott and Ben F. LuisiStructure of E. coli RNase E catalytic domain and its implications for RNA turnover and processing. Nature 437: 1187-1191 (2005). |
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16237448 | 2C0B 2BX2 2C4R |
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A Structural Element in the SARS Virus 3'-UTRM. P. Robertson, H. Igel, R. Baertsch, D. Haussler, M. Ares, Jr., and W. G. ScottThe Structure of a Rigorously Conserved RNA Element within the SARS Virus Genome Public Library of Science: Biology 3(1): e5. (2004). |
Paper |
15630477 | 1XJR |
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Link to Scott Lab PDF Reprint Collection.